Depression might be associated with accelerated cellular aging. However, does this result in an irreversible state or is the body able to slow down or recover from such a process? Telomeres are DNA‐protein complexes that protect the ends of chromosomes and generally shorten with age; and therefore index cellular aging. The majority of studies indicate that persons with depression have shorter leukocyte telomeres than similarly aged non‐depressed persons, which may contribute to the observed unfavorable somatic health outcomes in the depressed (...) population. Some small‐scale preliminary studies raise the possibility that behavioral or pharmacological interventions may either slow down or else reverse this accelerated telomere shortening, possibly through increasing the activity of the telomere‐lengthening enzyme telomerase. This paper covers the current state of evidence in the relationship between depression and the telomere‐telomerase system and debates whether depression‐related cellular aging should be considered a reversible process or permanent damage. (shrink)

Burgess, J.P. and Rosen, G. Subject with No ObjectElliott, R.Faking Nature.

The title of this lecture, as it stands now, is “Psychology and the Moral Problems of Our Time.” When I received the extremely flattering invitation to address you, the proposed title was “Light from Psychology on the Moral Problems of Our Time,” and as I am not by any means sure that Psychology throws a very clear light upon our problems, I begged that the title might be toned down. I say this at the outset, because I am afraid that (...) you may be disappointed by the emptiness of the psychological cupboards—at any rate so far as illumination upon the moral problems of our times is concerned, and if I were to appear before you claiming to be a torchbearer, you would be justified in accusing me of false pretences. (shrink)